Our clinical chemistry frozen serum and plasma products are unique because they are so close to the actual testing material taken from donors. This greatly reduces the matrix effects seen in lyophilized and other non CLIA approved clinical chemistry assurance materials. As a result, researchers and clinical chemistry analyte equipment manufacturers are able to utilize and create controls and calibrators that closely match the actual patient samples being tested and researched.
Custom frozen serum and plasma
Solomon Park has specializes in providing frozen serum and plasma with known levels of lipids and various other analytes. We will work closely with you to create custom pools tailored to your needs.
Fresh Whole Blood
In addition to frozen serum, we can supply your laboratory with fresh, whole blood. Solomon Park has a large database of known donors and we can provide you with a consistent product that meets your specifications.
Our laboratory can produce a broad range of urine pools, small or large, tailored to meet your project’s requirements.
Assessment of accuracy using lyophilized or other processed materials for the quantification of total or lipoprotein associated cholesterol presents technical difficulties which have been related to the matrix changes accompanying these manipulations. Frozen plasma and serum pools, however, have been used successfully for the external and internal quality control by the LRC program as well as by other major studies and are considered to be highly reliable materials for quality control or calibration.
For controls we offer four levels of LRC materials. Levels 1-4 contain 1.3 mL of human serum per vial. The samples can be used immediately or stored frozen at -70 degrees Centigrade until used.
The whole blood is obtained from apparently healthy donors with appropriate lipid levels. The blood is processed according to the CLSI document C37-A and either used immediately or frozen in bulk on the day of draw. Once sufficient volume is accumulated, pools are poured and filtered through 0.22μ hydrophobic sterile filters and aliquoted into 3 mL clear glass vials, stoppered with Teflon stoppers and capped. The materials are then quick frozen and stored at -70° Centigrade.
The samples are measured for all analytes at the Northwest Lipid Research Laboratories at the University of Washington in Seattle. Total high Density and Low Density Cholesterol are measured by the Abell-Kendall procedure. The LDL is analyzed using the Beta Quantification method. The triglyceride values are set by the enzymatic analysis. Apolipoproteins AI and B values are produced using IFCC standardized methods. All values are from duplicate analyses and are given as means.